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PPCM as a vascular disease

Researchers team at Beth Israel Deaconess Medical Center (BIDMC) have uncovered important new clues suggesting that peripartum cardiomyopathy (PPCM) may be a vascular disease, brought about by an imbalance of in the heart during the peripartum period, just prior to and immediately following delivery.


Angiogenic Proteins: Intercellular signaling peptides and proteins that regulate the proliferation of new blood vessels under normal physiological conditions. During pregnancy, a woman develops thousands of miles of blood vessels to support and nourish the growing baby.

Angiogenesis, the process by which the body forms new blood vessels, occurs in cancer, arthritis and other diseases, and in normal processes such as embryonic development, wound healing and ovulation.

Angiogenesis, and the role of zinc deficiency, could provide answers. Much medical research is being undertaken to find the cause of cardiovascular disease. eg http://www.abdn.ac.uk/sms/staffprofile.php?id=g.f.nixon is one researcher who is investigating 

1.      the role of PEA-15 in cardiovascular disease

2.      the effects of sphingolipids in blood vessel inflammation

3.      examining the mechanisms involved in sphingolipid regulation of angiogenesis

4.      the effects of dietary zinc deficiency in blood vessel function

If angiogenesis does play a role in the development of PPCM, then angiogenesis foods and information, found on http://www.angio.org/index.php, could well hold the key to preventing PPCM.

About Myheartsisters.com

Myheartsisters.com has been developed to raise awareness about heart failure in pregnancy (PPCM) and provide support for heart sisters through storytelling and friendship. How to Join - Join as a heart sister, cardiologist or relative of a deceased heart sister and add yourself to a map and directory listing.

Read PPCM Stories from heart sisters or read about PPCM Recovery

Published Tuesday, 15 May 2012 by Jeanee Andrewartha


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